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Home - Products - Metabolic Enzyme/Protease - AChE - (±)-Huperzine A

(±)-Huperzine A

CAS No. 120786-18-7

(±)-Huperzine A( Huperzine A )

Catalog No. M10769 CAS No. 120786-18-7

A naturally occurring sesquiterpene alkaloid that a reversible and selective inhibitor of acetylcholinesterase (AChE).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (±)-Huperzine A
  • Note
    Research use only, not for human use.
  • Brief Description
    A naturally occurring sesquiterpene alkaloid that a reversible and selective inhibitor of acetylcholinesterase (AChE).
  • Description
    A naturally occurring sesquiterpene alkaloid that a reversible and selective inhibitor of acetylcholinesterase (AChE); has been used for improving memory, cognitive and behavioral function in Alzheimer's disease; activates Wnt/β-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse model.Alzheimer's Disease Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Huperzine A
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    AChE
  • Recptor
    AChE
  • Research Area
    Neurological Disease
  • Indication
    Alzheimer Disease

Chemical Information

  • CAS Number
    120786-18-7
  • Formula Weight
    242.3162
  • Molecular Formula
    C15H18N2O
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC=C1C2CC3=C(C1(CC(=C2)C)N)C=CC(=O)N3
  • Chemical Name
    5,9-Methanocycloocta[b]pyridin-2(1H)-one, 5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (11E)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Burshtein G, et al. Planta Med. 2013 Mar;79(3-4):259-65. 2. Wang J, et al. J Neurosci Res. 2010 Mar;88(4):807-15. 3. Wang CY, et al. Neuropsychopharmacology. 2011 Apr;36(5):1073-89.
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