(±)-Huperzine A
CAS No. 120786-18-7
(±)-Huperzine A ( Huperzine A )
Catalog No. M10769 CAS No. 120786-18-7
A naturally occurring sesquiterpene alkaloid that a reversible and selective inhibitor of acetylcholinesterase (AChE).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 51 | Get Quote |
|
10MG | 83 | Get Quote |
|
25MG | 138 | Get Quote |
|
50MG | 205 | Get Quote |
|
100MG | 305 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product Name(±)-Huperzine A
-
NoteResearch use only, not for human use.
-
Brief DescriptionA naturally occurring sesquiterpene alkaloid that a reversible and selective inhibitor of acetylcholinesterase (AChE).
-
DescriptionA naturally occurring sesquiterpene alkaloid that a reversible and selective inhibitor of acetylcholinesterase (AChE); has been used for improving memory, cognitive and behavioral function in Alzheimer's disease; activates Wnt/β-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse model.Alzheimer's Disease Approved
-
SynonymsHuperzine A
-
PathwayMetabolic Enzyme/Protease
-
TargetAChE
-
RecptorAChE
-
Research AreaNeurological Disease
-
IndicationAlzheimer Disease
Chemical Information
-
CAS Number120786-18-7
-
Formula Weight242.32
-
Molecular FormulaC15H18N2O
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESCC=C1C2CC3=C(C1(CC(=C2)C)N)C=CC(=O)N3
-
Chemical Name5,9-Methanocycloocta[b]pyridin-2(1H)-one, 5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (11E)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Burshtein G, et al. Planta Med. 2013 Mar;79(3-4):259-65.
2. Wang J, et al. J Neurosci Res. 2010 Mar;88(4):807-15.
3. Wang CY, et al. Neuropsychopharmacology. 2011 Apr;36(5):1073-89.
2. Wang J, et al. J Neurosci Res. 2010 Mar;88(4):807-15.
3. Wang CY, et al. Neuropsychopharmacology. 2011 Apr;36(5):1073-89.
molnova catalog
related products
-
Vincosamide
Vincosamide, an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity.
-
Pseudocoptisine chlo...
Pseudocoptisine chloride is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity (IC50 = 12.8 μM).
-
AD-35 hydrochloride
A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates.